The Total theme, with the included WPBakery Visual Composer and Templatera plugins, creates an amazingly customizable responsive theme. Every page layout on your site can be tweaked if you wish, and you can build templates for different sections or categories of your posts and pages for an easy start on a new post or page.
The documentation pages are comprehensive and deserve a thorough read to allow you to better understand the possibilities. If you’re still stuck on something, I found the author is quick to respond to support requests.
As a side note, if you construct your WordPress in a sandbox (like MAMP Pro) you can create as many sites as you want without a need for a license for each one – a great way to test different designs. Of course, you’ll need a license when for each site that goes live.